At what age do puppies typically receive their first vaccination?

Puppies typically receive their first vaccination at around 7 weeks of age. This timing is crucial as it aligns with their developmental stage when they begin to lose maternal immunity. By this age, the immune system of the puppy is maturing and ready to respond to vaccinations effectively. The initial vaccinations are essential in providing protection against common infectious diseases such as distemper, parvovirus, and adenovirus. Early vaccination helps ensure that puppies develop immunity before they are exposed to other dogs or environments that pose a risk for these diseases.